Infliximab

Infliximab in ulcerative colitis

This paper critically reviews the evidence for established (5-aminosalicylic acid [5-ASA] compounds, corticosteroids, immunomodulators, calcineurin inhibitors) and emerging novel therapies-including biological therapies-directed at cytokines (eg, infliximab, adalimumab, certolizumab pegol) and receptors (eg, visilizumab, abatacept) involved in T-cell activation, selective adhesion molecule bloc...

Infliximab in psoriatic arthritis

Infliximab in ulcerative colitis

Infliximab, a monoclonal anti-TNF-alpha antibody, is commonly used for treatment of moderate to severe Crohn's disease (CD). Its role in the treatment for ulcerative colitis (UC) remains controversial. We review the role of TNF-alpha in the pathogenesis of UC and describe the randomized, double-blind, placebo-controlled trials and systematic reviews that assess the efficacy of infliximab in the...

Infliximab and nephrotic syndrome.

Infliximab is a chimeric tumor necrosis factor-alpha (TNF-alpha) monoclonal antibody, which has been used extensively in patients with rheumatoid arthritis and inflammatory bowel disease. It also appears to be effective in other conditions such as psoriasis and ankylosing spondylitis. The major side effect of infliximab is infection. Renal complications are uncommon and not well recognized. Thi...

Remsima, INN: infliximab